翻訳と辞書 Words near each other ・ Sindhudurg district ・ Sindhudurg Fort ・ Sindhughosh-class submarine ・ Sindhuja Rajaraman ・ Sindhukot ・ Sindarin ・ Sindarius Thornwell ・ Sindarli ・ Sindat ・ Sindatka ・ Sindbad (crater) ・ Sindbad Alibaba and Aladdin ・ Sindbad Amusement Park ・ Sindbad Hotel Complex and Conference Center ・ Sindbad-Nameh ・ Sindbis virus ・ Sinde ・ Sinde (ward) ・ Sindecade ・ Sindechites ・ Sindecuse Museum of Dentistry ・ Sindee Coxx ・ Sindel ・ Sindel (village) ・ Sindel Point ・ Sindelar ・ Sindelbach ・ Sindelbach (Körsch) ・ Sindelfingen ・ Sindell v. Abbott Laboratories Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Sindbis virus ： ウィキペディア英語版 Sindbis virus Sindbis Virus (SINV) is a member of the ''Togaviridae'' family, in the alphavirus subfamily. The virus was first isolated in 1952 in Cairo, Egypt. The virus is transmitted by mosquitoes (''Culex'' spp.) SINV causes sindbis fever in humans and the symptoms include arthralgia, rash and malaise. Sindbis fever is most common in South and East Africa, Egypt, Israel, Philippines and parts of Australia. Sindbis virus is an "arbovirus" (arthropod-borne) and is maintained in nature by transmission between vertebrate (bird) hosts and invertebrate (mosquito) vectors. Humans are infected with Sindbis virus when bitten by an infected mosquito. SINV has been linked to Pogosta disease in Finland.,〔Kurkela S, Manni T, Vaheri A, Vapalahti O. (Causative agent of Pogosta disease isolated from blood and skin lesions ), Emerg Infect Dis (on the Internet ). Published 2004 May. (accessed 2007-10-16)〕 Ockelbo disease in Sweden and Karelian fever in Russia. ==Virus structure, genome and replication== Sindbis viruses are enveloped particles with an icosahedral capsid. Its genome is a single stranded RNA approximately 11.7kb long. It has a 5' cap and 3' polyadenylated tail therefore serves directly as messenger RNA (mRNA) in a host cell. The genome encodes four non-structural proteins at the 5' end and the capsid and two envelope proteins at the 3' end. This is characteristic of all Togaviruses. Replication is cytoplasmic and rapid. The genomic RNA is partially translated at the 5’ end to produce the non-structural proteins which are then involved in genome replication and the production of new genomic RNA and a shorter sub-genomic RNA strand. This sub-genomic strand is translated into the structural proteins. The viruses assemble at the host cell surfaces and acquire their envelope through budding. A non-coding RNA element has been found to be essential for Sindbis virus genome replication. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sindbis virus」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.